F18F-18

F-18是正电子发射断层扫描（PET）中使用最广泛的放射性同位素。它在肿瘤学、心脏病学和神经学领域应用广泛。这种放射性核素最常见的示踪剂是葡萄糖类似标记化合物：氟代脱氧葡萄糖（FDG）。

生产 F-18，
我们建议采用以下生产路径：

推荐
Cyclone:
Cyclone^® KIUBE
下载宣传册
Cyclone^® KIUBE 的能量为18 MeV，在¹⁸F的大产能生产方面具有高性价比。该回旋加速器可以升级，因此您可以从较小的投资开始，同时随着时间的推移能够保持提高PET中心产能的能力，2小时运行最多可生产30 Ci的 ¹⁸F。

更多关于Cyclone^® KIUBE的信息

靶：
Nirta ^® 液体靶
Nirta^® ¹⁸F锥形液体靶使用市场上最少量的富氧水可实现最高束流强度。

更多关于Nirta^® 液体靶的信息

化学：
Synthera^® +
Synthera^® +是一款全自动合成器，用于标记18F化合物（[¹⁸F]FDG、[¹⁸F]FPSMA-1007, [¹⁸F]NaF、 [¹⁸F]FET; [¹⁸F]FLT、 [¹⁸F]FMISO、 [¹⁸F]FCH 等）。它结合IFP™加载器系统和自动弹出功能，可多次运行生产不同的示踪剂。

更多关于Synthera^® 扩展模块和Synthera^® +的信息
推荐
Cyclone:
Cyclone^® KEY
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Cyclone^® KEY 的能量为9.2MeV，运行 2 小时可生产多达3 Ci的F-18。

更多关于Cyclone^® KEY的信息

靶：
Nirta ^® 液体靶
Nirta^® ¹⁸F锥形液体靶使用市场上最少量的富氧水可实现最高束流强度。

更多关于Nirta^® 液体靶的信息

化学：
Synthera^® +
Synthera^® +是一款全自动合成器，用于标记¹⁸F化合物（[¹⁸F]FDG、[¹⁸F]FPSMA-1007、 [¹⁸F]NaF、 [¹⁸F]FET； [¹⁸F]FLT、 [¹⁸F]FMISO、[¹⁸F]FCH 等）。它结合IFP™加载器系统和自动弹出功能，可多次运行生产不同的示踪剂。

更多关于Synthera^® 扩展模块和Synthera^® +的信息
替代方案
Cyclone:
Cyclone^® IKON
下载宣传册
¹⁸F也可以在Cyclone^® IKON上以可变能量生产。

更多关于Cyclone^® IKON的信息

靶：
Nirta ^® 液体靶
Nirta^® ¹⁸F锥形液体靶使用市场上最少量的富氧水可实现最高束流强度

更多关于Nirta^® 液体靶的信息

化学：
Synthera^® +
Synthera^® +是一款全自动合成器，用于标记¹⁸F化合物（[¹⁸F]FDG、[¹⁸F]FPSMA-1007、 [¹⁸F]NaF、 [¹⁸F]FET； [¹⁸F]FLT、[¹⁸F]FMISO、 [¹⁸F]FCH 等）。它结合IFP™加载器系统和自动弹出功能，可多次运行生产不同的示踪剂。

更多关于Synthera^® 扩展模块和Synthera^® +的信息
替代方案
Cyclone:
Cyclone^® 30 XP
下载宣传册
¹⁸F也可以在Cyclone^® 30 XP上以可变能量生产。

更多关于Cyclone^® 30 XP的信息

靶：
Nirta ^® 液体靶
Nirta^® ¹⁸F锥形液体靶使用市场上最少量的富氧水可实现最高束流强度

更多关于Nirta^® 液体靶的信息

化学：
Synthera^® +
Synthera^® +是一款全自动合成器，用于标记18F化合物（[¹⁸F]FDG、[¹⁸F]FPSMA-1007、 [¹⁸F]NaF、 [¹⁸F]FET； [¹⁸F]FLT、 [¹⁸F]FMISO、 [¹⁸F]FCH 等）。它结合IFP™加载器系统和自动弹出功能，可多次运行生产不同的示踪剂。

更多关于Synthera^® 扩展模块和Synthera^® +的信息

科学出版物

查看更多出版物

F18F-18

生产 F-18，我们建议采用以下生产路径：

Cyclone:

靶：

化学：

Cyclone:

靶：

化学：

Cyclone:

靶：

化学：

Cyclone:

靶：

化学：

科学出版物

Al[18F]F-NOTA-Octreotide Is Comparable to [68Ga]Ga-DOTA-TATE for PET/CT Imaging of Neuroendocrine Tumours in the Latin-American Population

A simplified protocol for the automated production of 2-[18F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine ([18F] nifene) on an IBA Synthera® module

CRITICAL POINTS FOR IMPROVEMENT OF PERFORMANCE IN A SUMMARY OF MODULE SYNTHERA 18FDG.

Automated syntheses of N-SUCCINIMIDYL 4-[18F]Fluorobenzoate ([18F]SFB) AND N-[2-(4-18F-Fluorobenzamido) Ethyl]maleimide([18F]FBEM) using a customised IBA synthetiser

Development of a Radiosynthesizer Module Designed to Produce Florbetapir F 18 (18F-AV-45) for Clinical Trials

Fully automated synthesis of apoptosis probe PET-18F-ML-10 with a multipurpose chemistry platform

Nucleophilic Labeling Reactions on Synthera: A Multipurpose Synthesis Platform

Automated radiosynthesis of [18F]FAZA with Synthera radiochemistry box

Automated synthesis of [18F] fluoroacetate using a compact FDG synthesizer

Automated production of [18F] 2-fluoroethyl azide and a thymidine analogue using the Synthera module

A simplified protocol for the automated production of succinimidyl 4‐[18F] fluorobenzoate on an IBA Synthera module

A rapid and simple automated synthesis of 18F-MISO

Nucleophilic labeling reactions on a multipurpose synthesis platform.

Optimisation of the automated synthesis of 18F-FMISO using the Synthera[registered] Platform

Nucleophilic labeling reactions on a multipurpose synthesis platform.

Optimization of [18F]-FDG production with terminal sterilization by autoclave.

Synthesis of stereochemically pure 18F-cis-4-fluoro-L-proline on an automated synthesis module.

Routine production in a GMP environment of multiple 18F-radiopharmaceuticals on a disposable-based fully automated platform

Fully automated synthesis of 18F-FET using the Synthera[registered] Platform

Automated synthesis of 18F-labeled ligands for pre- and postsynaptic PET imaging of the dopaminergic system using IBA Synthera modules

Fully automated production of [18F]fluoroacetate on IBA Synthera platform

Improved synthesis and purification of meta-[18F]fluorobenzylguanidine (mFBG) for clinical use

Synthesis of 18F-L-FDOPA via Nucleophilic Pathway on IBA's Synthera®

Combining commercial production of multi-products in a GMP environment with Clinical & R&D activities

Synthesis and purification of hexadecyl-4-[18F]fluorobenzoate using the cassettebased Synthera® module for labeling exosomes and macromolecules

Optimization of final product DMAE content is 18F-Fluorocholine process using double IBA Synthera® process

Routine Production of [18F]PSMA-1007 and First Clinical Experience in Staging of Prostate Cancer Patients

A high molar activity 18F-labeled TAK-875 derivative for PET imaging of pancreatic β- cells

A simplified radiosynthesis of [18F]MK‐6240 for tau PET imaging

Combining multi-product commercial production in a GMP environment with Clinical & R&D activities

The new bern cyclotron laboratory for radioisotope production and research

Performance of IBA new Conical shaped Niobium [18O] water Targets

Performance of IBA new Conical shaped Niobium [18O] water Targets

18F- saturation yield in Large Volume cylindrical IBA target

Development of a Krypton Target for Cyclone-30 at KFSH&RC

Modernization program of Cyclone®18/9 at ASAN Medical Center, Seoul

A New Powerful Compact Cyclotron

Analysis of Radioisotopic Metal Impurities Generated in (O-18) H2O during F-18 Production with Cyclotron

Experimental and Monte Carlo characterization of radionuclidic impurities originated from proton irradiation of [18O]H2O in a modern medical cyclotron

The methodology of characterization of neutron leakage field from PET production cyclotron for experimental purposes

Automated cassette-based synthesis of [18F]FAPI-74 via [18F]AlF strategy for routine production in a GMP environment

生产 F-18，
我们建议采用以下生产路径：

A simplified protocol for the automated production of 2-[18F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine ([18F] nifene) on an IBA Synthera^® module

Automated syntheses of N-SUCCINIMIDYL 4-[¹⁸F]Fluorobenzoate ([¹⁸F]SFB) AND N-[2-(4-¹⁸F-Fluorobenzamido) Ethyl]maleimide([^18F]FBEM) using a customised IBA synthetiser

Development of a Radiosynthesizer Module Designed to Produce Florbetapir F 18 (¹⁸F-AV-45) for Clinical Trials

Fully automated synthesis of apoptosis probe PET-¹⁸F-ML-10 with a multipurpose chemistry platform

Automated radiosynthesis of [¹⁸F]FAZA with Synthera radiochemistry box

Optimisation of the automated synthesis of 18F-FMISO using the Synthera^[registered] Platform

Synthesis of stereochemically pure ¹⁸F-cis-4-fluoro-L-proline on an automated synthesis module.

Fully automated synthesis of 18F-FET using the Synthera^[registered] Platform

Automated synthesis of ¹⁸F-labeled ligands for pre- and postsynaptic PET imaging of the dopaminergic system using IBA Synthera modules

Fully automated production of [¹⁸F]fluoroacetate on IBA Synthera platform

Synthesis of 18F-L-FDOPA via Nucleophilic Pathway on IBA's Synthera^®

Synthesis and purification of hexadecyl-4-[18F]fluorobenzoate using the cassettebased Synthera^® module for labeling exosomes and macromolecules

Optimization of final product DMAE content is 18F-Fluorocholine process using double IBA Synthera^® process

Performance of IBA new Conical shaped Niobium [¹⁸O] water Targets

Performance of IBA new Conical shaped Niobium [¹⁸O] water Targets

Modernization program of Cyclone^®18/9 at ASAN Medical Center, Seoul